The fast multipole method (FMM) is an efficient algorithm for what is known as "N-body problems." I will present a new scalable algorithm and a new implementation of the kernel-independent fast multipole method, in which both distributed memory parallelism (using MPI) and shared memory/SIMD parallelism (via GPU acceleration) are employed. I will conclude my talk by discussing the direct numerical simulation of blood flow in the Stokes regime using the FMM. I will describe simulations with 200 million red blood cells, an improvement of four orders of magnitude over previous results. Bio: George Biros holds Associate Professor appointments with the Schools of Computational Science and Engineering at Georgia Tech and The Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory University. Prior to joining Georgia Tech, he was an assistant professor in Mechanical Engineering and Applied Mechanics, Bioengineering and Computer and Information Science at the University of Pennsylvania. He received his BS in Mechanical Engineering from Aristotle University Greece (1995), his MS in Biomedical Engineering from Carnegie Mellon (1996), and his PhD in Computational Science and Engineering also from Carnegie Mellon (2000). He was a postdoctoral associate at the Courant Institute from 2000 to 2003.