Julia Ling - Citrine Informatics Interpretability lets practitioners diagnose poor performance in their machine learning models and uncover sample bias in their training sets. Furthermore, in scientific contexts, it sparks new physical insights for scientists and engineers, enabling human learning alongside machine learning. In this talk, I will describe three different approaches to interpretability. I will start with the domain of turbulence modeling for turbomachinery applications and describe how spatiallyresolved feature importance visualizations can drive deeper understanding of the physical mechanisms at work in turbulent flows. I will then move on to the application of materials development, explaining how non-linear sensitivity analysis can be used to visualize the predicted performance of candidate materials. Finally, I will describe approaches to quantifying the performance of sets of candidate materials to better guide project direction.