Susan Coppersmith - University of Wisconsin-Madison, Physics Motivated by the tremendous scalability of classical silicon electronics, we are working to build a large-scale quantum computer using silicon technology similar to that used to build current classical computers, specifically, electrically-gated quantum dots in silicon-germanium heterostructures. This talk will discuss the fundamental physics and materials science challenges that arise, and how close coupling between theory and experiment has enabled substantial progress towards the goal of high fidelity qubits. Prospects for further development will also be discussed.