The BD Innovation Hubs and related investments are intended to accelerate and strengthen the data ecosystem. To address this goal, the mission of the Midwest Big Data Hub (MBDH) is to develop effective cross-sector networks ready to utilize Data Science and Big Data approaches to solve problems of regional and societal interest. We are a growing organization interested in developing partnerships, and improving access and use of data for scientific discovery and data-to-decision systems. Based at the National Center for Supercomputing Applications (NCSA) at the University of Illinois in Urbana-Champaign, the MBDH is a consortium that includes funded collaborators at Indiana University, Iowa State University, the University of Michigan, and the University of North Dakota. The 12 states served by the MBDH are: Illinois, Indiana, Iowa, Kansas, Michigan, Minnesota, Missouri, Nebraska, North Dakota, Ohio, South Dakota, and Wisconsin. This overview will highlight current projects and evolving activities for agriculture and food-energy-water.